Prevalence and Associations of Preeclampsia and Dyslipidemia Among Pregnant Women in Northern Ghana

Ahenkan Yeboah; Gideon Adu-Bonsu

doi:10.64229/xgewtk53

Authors

Ahenkan Yeboah Department of Medical Biochemistry, University of Ghana, Accra, Ghana Author
Gideon Adu-Bonsu Department of Biotechnology and Molecular Biology, University for Development Studies, Tamale, Ghana Author

DOI:

https://doi.org/10.64229/xgewtk53

Keywords:

Preeclampsia, Dyslipidemia, Neonatal, Body Mass Index

Abstract

Preeclampsia (PE) and dyslipidemia are major factors in maternal morbidity, especially in resource-constrained environments. This study examined the prevalence and correlations of preeclampsia and dyslipidemia in pregnant women in rural Ghana to guide interventions for enhanced maternal health outcomes. A cross-sectional study was conducted at the War Memorial Hospital in Navrongo, Ghana, enrolling 70 pregnant women in their third trimester. Preeclampsia was characterized by hypertension and proteinuria, whereas dyslipidemia was determined through lipid profile analysis. Data were gathered via clinical assessments and laboratory investigations, and associations were analyzed using chi-square tests, with a p-value < 0.05 being statistically significant. The incidence of preeclampsia was 8.57%, whereas 36% of patients were diagnosed with dyslipidemia, predominantly hypertriglyceridemia and hypercholesterolemia. Significantly, 50% of women with preeclampsia also exhibited dyslipidemia. Notable correlations were identified between preeclampsia and maternal age (p < 0.05) as well as physical activity level (p < 0.0001). Dyslipidemia had a strong correlation with gestational weight increase (p = 0.036) and dietary patterns (p = 0.012). No substantial correlations were identified between preeclampsia or dyslipidemia with BMI, parity, or familial history. This study underscores the relationship between lipid metabolism and hypertension problems during pregnancy, stressing the necessity for early screening and customized therapies. Incorporating lipid profile assessment and nutritional guidance into prenatal care may substantially enhance maternal health outcomes, especially in resource-limited environments.

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Prevalence and Associations of Preeclampsia and Dyslipidemia Among Pregnant Women in Northern Ghana

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